Chloroquine maculopathy ppt

Discussion in 'Reliable Pharmacy' started by www.links, 17-Mar-2020.

  1. alexor XenForo Moderator

    Chloroquine maculopathy ppt


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    A woman aged 28 years with systemic lupus erythematous and abnormal kidney function, treated with 45 mg/kg hydroxychloroquine daily for 15 years cumulative dose 1369 g, presented with bilateral progressive central vision loss for 2 months. The patient had no known previous exposure to chloroquine. Best corrected visual acuity was 20/40 in her right eye and 20/30 in her left eye. Funduscopy. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Chloroquine and hydroxychloroquine both belong to the quinolone family and share similar clinical indications and side effects, including retinal toxicity. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine maculopathy ppt

    Chloroquine Retinopathy - an overview ScienceDirect Topics, Chloroquine - FDA prescribing information, side effects.

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  7. Mar 15, 2019 Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ.

    • Chloroquine and Hydroxychloroquine Toxicity Clinical Presentation.
    • Hydroxychloroquine Plaquenil Toxicity and Recommendations..
    • Chloroquine - FDA prescribing information, side effects and uses.

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. Recent studies estimate that about 1% of patients develop toxic maculopathy after 5 years of treatment with plaquenil or chloroquine. The risk of maculopathy is associated with cumulative dose level of 1,000 grams and it usually takes 5-7 years for patients on the standard treatment of 250-400 milligrams per day to reach that level. Jan 05, 2020 Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease

     
  8. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Common and Rare Side Effects for Plaquenil Oral Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus
     
  9. mlm-lider Moderator

    Hydroxychloroquine Plaquenil Side Effects & Dosage for. It is similar to chloroquine Aralen and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. Its mechanism of action is unknown. Malarial parasites invade human red blood cells.

    Chloroquine Dose For Rheumatoid Arthritis
     
  10. Lokki Guest

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