I know I had never heard of it until my rheumatologist said that is what I have...along w/osteoarthritis and fibromyalgia. My blood tests are negative for RF but my CRP test was above normal. Ai Yi Yi Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells (these are messengers for your immune system, if you will) from interacting with your T-Cells (a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders). So, he started me on 400 mg of Plaquenil a day and he just upped it to 600 mg a day. As I said previously, my Rheumatologist now says it is inflammatory osteoarthrits. Why am I taking Plaquenil, which does help tremedously BTW, if I don't have RA or Lupus. This "dendritic deactivation" (I made that phrase up) helps reduce your immune system being silly and inflaming your joints. Plaquenil causing alopecia Sjogrens plaquenil rash Plaquenil synthesist Plaquenil eye pain Currently on plaquenil and tramadol and have had no relief. My main concern is my joints are breaking down. Knees and ankles. Had a knee replacement at the age of 28 and I am now 40 and looking at needing ankle fusions. The results showed an average bone density growth of 10% in 8 months and 51% in 34 months. Not a drug. neutraceutical or bioceutical. I think Life Extension has a version too. Can get at various online companies and Amazon. I’m taking the highest dose they make. Also starting low dose hormone replacement therapy. I was wondring about risks related to knee joint replacement surgery in someone who has Lupus. I also hypothyroidism and sjorgens desease as well. I recently had to have an iron infusion due to being seriuosly enemic. I have been taking plaquinil for the last year and recenlty stared Cymbalata as well. My sister was dx'd with Inflammatory Arthritis and Plaquenil sent her into remission some years ago now. I also take meds for high bp, asthma and high cholesterol. Plaquenil and knee replacement Inflammatory Osteoarthritis And Plaquenil, Starting an osteoporosis drug? Here's what you need to know. Plaquenil visual field asianDecreased libido plaquenilPlaquenil rash images Knee joint replacement is found among people who take Rituxan, especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Systemic lupus erythematosus. Will you have Knee joint replacement with Rituxan - eHealthMe. Surgery risk for knee joint replacement w/ lupus" Lupus.. Perioperative Management of Medications Used in the.. Use in patients with psoriasis may precipitate a severe attack of psoriasis; use with caution Postmarketing cases of life-threatening and fatal cardiomyopathy reported with use of hydroxychloroquine as well as of chloroquine Irreversible retinal damage observed in some patients who had received hydroxychloroquine sulfate; The definitive treatment for advanced joint destruction in the late stages of rheumatoid arthritis can be successfully treated with total joint arthroplasty. Total knee arthroplasty has been shown to be a well-proven modality that can provide pain relief and restoration of mobility for those with debilitating knee arthritis. It is important for rheumatologists and orthopedic surgeons alike to. Nov 26, 2014 Platelet rich plasma PRP is a relatively new therapy that has been successfully used in the fields of sports medicine and trauma. 1 PRP therapy is the use of a patient’s own blood plasma that has been enriched with his or her platelets and injected into an area of damaged tissue.