I started Plaquenil last week and so far the side effects are dizziness, nausea and tummy feeling weird. I was just wondering has long it takes to adjust and if taking twice the dose will result in higher discomfort. Plaquenil and risperdal Plaquenil for lyme Alcohol and plaquenil? By curious101. New Reply Follow New Topic. curious101 over a year ago. Can you drink alcohol while taking Plaquenil? I don't drink everyday, but have had some drinks while on NSAIDS and Prednisone and have not had any bad effects. What happens with Plaquenil? I'm terrible at remembering. I have to take Plaquenil, Naturethroid and Vitamin D, everyday. My other concern, I'm a wine drinker, a couple of glasses a week, mostly weekends or after a long day at work. I was researching on wine alcohol use while on Plaquenil and I'm a bit confused. I'm also taking Naturethoid. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Avoid alcohol while taking this medication. Also, any tips on how to keep up with taking them on schedule? I have to take Plaquenil, Naturethroid and Vitamin D, everyday . I'm having lots of trouble falling asleep (been having it for a while), not sure if it's getting worse due to the pills. How longbto take plaquenil after alcohol Plaquenil Indications, Side Effects, Warnings -, Plaquenil & Wine Dose of plaquenil for rheumatoid arthritis Symptoms can start to improve in one to two months, but it may take up to six months before the full benefits of this medication are experienced. Side Effects Hydroxychloroquine typically is very well tolerated. Hydroxychloroquine Plaquenil. Hydroxychloroquine Side Effects, Dosage, Uses, and More. What next if plaquenil doesn't work? -. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Alcohol interaction is reported only by a few people who take Plaquenil. We study 48,911 people who have side effects while taking Plaquenil from Food and Drug Administration FDA. Among them, 3 have Alcohol interaction. Find out below who they are, when they have Alcohol interaction and more.