It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine phosphate 250 mg side effects Keflex and plaquenil I notice a difference in my fatigue and joint pain. I think even though they say it doesn't make a difference, I feel wierd if I don't take my plaquenil sometimes. Almost as if there is a little withdraw going on. I feel sluggish and more nauseated. May 25, 2010 Hi! I think Plaquenil is the cause of my extreme fatigue too. I am not anemic at this time and I get exhausted just trying to get through the day. I have also been on Plaquenil about three months. All of my arthritis swelling and pain are gone, but the fatigue will not let up! Hope things change for you. Nausea, vomiting, stomach upset, cramps, loss of appetite, diarrhea, tiredness, weakness or headache may occur the first several days as your body adjusts to the medication. If these effects continue or become bothersome, inform your doctor. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil makes my body ache Common and Rare Side Effects for Plaquenil Oral, Is extreme fatigue a side effect of Plaquenil? Hydroxychloroquine urine colorAzathioprine and plaquenilChloroquine uk pharmacyPlaquenil and oral thrushPlaquenil sudden tightness neck pain It might be coincidence but since on the plaquenil, I have noticed a growth spurt of hair especially at the hairline. It has been a lot thinner these past few years. inflammator arthritis, asthma, skin scleroderma, VSL#3 probiotic, Vit. Blood test positive for Crohn's via prometheus ibd serology panel ASCA. What next if plaquenil doesn't work?. PLAQUENIL Patient Assistance Program. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Dry skin; Loss of appetite; Abdominal bloating; Upset stomach; Stomach cramps; Retinal damage – There is a small chance that retinal damage will occur while taking hydroxychloroquine Plaquenil or chloroquine Aralen. Then I discovered that plaquenil can have a side effect of hair loss. But I also know that lupus can too. I brought this up with my doctor and all he said was to take vitamin B. which is silly because I'm already on two different multivitamins. My next appt isn't until the end of August and my formerly thick hair is now pathetically thin. Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.