While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Plaquenil tabs Can plaquenil lower blood pressure These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. I have been on Plaquenil for several years, first the generic Plaqenil has no coating to protect your stomach lining. If you have side affects first try brand. I know Dr. s Say there is no difference."But" composition of the drug may not affect the effectiveness of drug but it will affect the way it is absorbed in your system. Aug 26, 2016 Plaquenil is supposed to stay in your system for 1-2 months after you stop taking it. Try to rest, stay hydrated and away from sick ppl for now and hopefully you will not have any issues I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. How long to try plaquenil Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil User Reviews for Sjogren's Syndrome at Hydroxychloroquine alternativesPlaquenil visual fieldPlaquenil action User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Plaquenil User Reviews for Rheumatoid Arthritis at. Stopping Plaquenil - General Discussion - Life With Lupus. How long does it take for plaquenil to work - Answers. Re Plaquenil - Can It Work Quickly? I tried to get on Plaquenil years ago, and couldn't tolerate it, but now I'm thinking there might be a lessor dose I should try. I'm new to the area, so don't have a rheumy yet. I'm on plaquenil alone, I'm trying to hold the line and put off methotrexate as long as possible. The Plaquenil is supposed to kick in in 3 to 6 months. I think it was 8 months for me. One day I was congratulating myself for getting so many things done and I realised that the days had been getting better without my noticing. How long does it take for plaquenil to work - Kim.luck. I'm crossing my fingers with you. Hopefully you can get back to Plaquenil and it will work for you. I had almost no side effects except for an minor upset stomach if I didn't eat when taking the pill.