It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Can plaquenill build up and cause migraines Plaquenil for ra Nausea, vomiting, stomach upset, cramps, loss of appetite, diarrhea, tiredness, weakness or headache may occur the first several days as your body adjusts to the medication. If these effects continue or become bothersome, inform your doctor. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. I started to take plaquenil for my mild lupus about 3 weeks ago and I noticed that I am having less appetite these days. I get hungry during dinner time, but all the foods does not taste as good as before. It feels weird! Eating delicious food was one of the joy of my life. The food that I used to love does not taste as good as before. humm. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil appetite loss Plaquenil & weight loss Lupus Forums at The Lupus Site, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil birthHydroxychloroquine widely useDoes plaquenil cause dark urineAralen pastillaCan i take plaquenil and benadryl I had taken Plaquenil for 4 yrs and had quit due to loss of appetite and weakness, but was on hormone therapy. This year my ins decided not to pay for my hormones, and sure to the increase in pain and elevated liver enzymes from Methotrexate, I started back on the Plaquenil. Nausea and loss of appetite - Sjogren's Syndrome Support. Little appetite with plaquenil?" Lupus Community.. Plaquenil & Weight Gain/Loss -. Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Yes, Plaquenil causes both weight loss and loss of appetite. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.