It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Guidelines for plaquenil screening Hydroxychloroquine cancer Plaquenil 200mg cost It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. How to use Plaquenil Hydroxychloroquine is usually taken with food. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Plaquenil works rheumatoid arthritis Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine Side-effects, uses, time to work Teva-chloroquine phosphateCan you take plaquenil help hair growthHydroxychloroquine 400 mg tabletsPlaquenil and parkinsons What next if plaquenil doesn't work? Support Forums Rheumatoid Arthritis New Topic Reply. for me methotreaxte and plaquenil does't work and i' intonate of sulfa so i am started embrel which states you have to have tried 2 of 3 meds and methotrexate is 1 of them. good luck What next if plaquenil doesn't work?. Hydroxychloroquine Plaquenil. Hydroxychloroquine Plaquenil Success, Reviews and Side.. What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Plaquenil works well, but very slowly. You will need to give it at least a 6 months trial, and don't expect much in the way of results for a couple of months. After that, you'll probably look back and realize one day that you just don't feel as sore as you did three or four months back. Rated Hydroxychloroquine for Rheumatoid Arthritis Report Plaquenil was a miracle drug for me. It began to work in 3 weeks and within 6 months my inflammation had gone from over 40 to 5.5.