Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What type muscle weakness with plaquenil Plaquenil for granuloma annulare Plaquenil lo loestrin fe Chloroquine fisher May 07, 2012 Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How long do plaquenil side effects last Common and Rare Side Effects for Plaquenil Oral, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Anti malarial medication hydroxychloroquineDrugs for rheumatoid arthritis starting with hydroxychloroquinePlaquenil bone marrow depression Side effects Hydroxychloroquine Plaquenil is one of the safest drugs in medicine. Serious side effects are rare & routine blood tests are not required. Allergy new skin rashes is unusual but it means ruling our future use. Commoner, usually mild, side effects are indigestion, ‘gurgly tummy’, diarrhoea & headache. Plaqunil rash -. Rx Side Effects New Plaquenil Guidelines and More.. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. If side effects do occur, they are usually minor and last only for a short period of time. Potential side effects of anti-malarial drugs include Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish.