Chloroquine phosphate poisoning

Discussion in 'Canadian Pharcharmy Online' started by maneak, 14-Mar-2020.

  1. KonstantinMiha Moderator

    Chloroquine phosphate poisoning


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    CHLOROQUINE PHOSPHATE, USP DESCRIPTION ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug. Page 2 of 6 Chloroquine phosphate SAFETY DATA SHEET 2.3 Harmful if swallowed. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation or skin absorption. May cause eye, skin, or respiratory system irritation. May cause damage to {organs} through prolonged or repeated exposure. Chloroquine phosphate comes as a tablet to take by mouth. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Your doctor will tell you how many tablets to take for each dose. One dose is taken beginning 2 weeks before traveling to an area.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine phosphate poisoning

    PDF Chloroquine poisoning - ResearchGate, SAFETY DATA SHEET Page 1 of 6 Chloroquine phosphate Revision

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  5. Feb 20, 2013 The Material Safety Data Sheet MSDS for chloroquine phosphate is difficult to interpret. Much of the toxicity data listed were derived from chronic exposure in humans taking the drug for control of malaria; retinal damage, nervous system disruption, and liver damage.

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    The therapeutic dose of chloroquine phosphate is 500 mg once a week for malaria prophylaxis or 2.5 g over 2 days for treatment of malaria. Deaths have been reported in children after ingesting one or two tablets—doses as low as 300 mg; the lethal dose of chloroquine for an adult is estimated at 30–50 mg/kg. Chloroquine Phosphate. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I.

     
  6. goolge Guest

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil and Pregnancy - Antibiotics Home Page Systematic review of hydroxychloroquine use in pregnant. Medicines for the Prevention of Malaria While Traveling.
     
  7. VoltAge Well-Known Member

    Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. Plaquenil side effects - kidney problems? - When lupus targets the kidneys Lupus Foundation of America Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
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  9. dimdim25 Moderator

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