It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Interactions between plaquenil and methotrexate Plaquenil mot malaria Can plaquenil treat psoriasis Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. The recommended hydroxychloroquine dosage for treating rheumatoid arthritis is 400 to 600 mg daily. For the treatment of lupus, the suggested dose is 400 mg once or twice daily. To prevent malaria in adults traveling to an area of high risk, the recommended dosage is 400 mg once weekly, starting two weeks before anticipated exposure. According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with arthritis. It can also reduce the incidence of joint damage, thus lessening the risk of developing a long-term disability from complications of RA. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil malaria prevention Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine Dosage - Malaria Home Page Plaquenil and juvenile arthritisHydroxychloroquine plaquenil and surgery Hydroxychloroquine also known as hydroxychloroquine sulfate is an arthritis medicine that also can be used to prevent malaria. Medicines for the Prevention of Malaria While Traveling.. RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. The recommended Plaquenil dosage for malaria prevention is 400 mg once weekly, starting two weeks before the anticipated exposure. The usual starting dosage for treating lupus is 400 mg once or twice a day, and the recommended starting dose for the treatment of rheumatoid arthritis is 400 to 600 mg daily. Primaquine phosphate has two distinct uses for malaria prevention primary prophylaxis and presumptive antirelapse therapy also called terminal prophylaxis. When taken for primary prophylaxis, primaquine should be taken 1–2 days before travel to malarious areas, daily, at the same time each day. In the treatment of SLE, Plaquenil is widely regarded as a cornerstone drug in the management of skin & arthritis symptoms. History of Antimalarials The history of antimalarials dates back to the 1630s in Peru, where, in all likelihood, malaria was not endemic, and an extract from the “fever tree,” which grew on the eastern slopes of the.