Hydroxychloroquine induced rash

Discussion in 'Canadian Drug' started by xoctmakc, 19-Mar-2020.

  1. stunt Well-Known Member

    Hydroxychloroquine induced rash


    B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions.

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    S ir, Hydroxychloroquine is widely used in the treatment of rheumatoid arthritis and systemic lupus erythematosus, with very few reported side‐report the case of a 65‐yr‐old woman who developed Stevens–Johnson syndrome 2 weeks after commencing treatment with hydroxychloroquine. Drug-induced photosensitivity occurs when certain photosensitising medications cause unexpected sunburn or dermatitis a dry, bumpy or blistering rash on sun- exposed skin face, neck, arms, backs of hands and often lower legs and feet. The rash may or may not be itchy. Medications can also cause onycholysis the nail plate lifting off the. Within 8 months of treatment, with moderate clinical response, she developed the skin rash depicted in Fig. 1, after prolonged exposure to sunlight during gardening. At the beginning, the skin had an erythematous colour, but gradually turned into a dark-pigmented rash.

    B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100).

    Hydroxychloroquine induced rash

    A Case Report on Hydroxychloroquine Drug Induced Maculopappular Rashes., Drug-induced photosensitivity DermNet NZ

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  6. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative.

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    Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. It is a known adverse reaction to quinine; hydroxychloroquine, as a synthetic derivative of this parent compound, may also put patients at risk of this complication. However, reports of hydroxychloroquineinduced TTP are extremely rare in the literature. Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1

     
  7. WebCults Well-Known Member

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine Uses, Dosage & Side Effects - Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil - how long for side effects to subside?
     
  8. Sky Dreamer XenForo Moderator

    Atovaquone/Proguanil (Malarone) Adults: 1 adult tablet daily. List of Malaria Prevention Malaria Prophylaxis Medications. Chloroquine Dosage Guide with Precautions - Chloroquine Oral Uses, Side Effects, Interactions, Pictures.
     
  9. Alexyz Moderator

    Hydroxychloroquine MotherToBaby In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk.

    Chloroquine vs Hydroxychloroquine Comparison -