It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Lyrica and plaquenil Ok to stop taking hydroxychloroquine Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Medical use. Hydroxychloroquine treats malaria, systemic lupus erythematosus, rheumatic disorders like rheumatoid arthritis, porphyria cutanea tarda, and Q fever. In 2014, its efficacy to treat Sjögren syndrome was questioned in a double-blind study involving 120 patients over a 48-week period. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Systemic Lupus Erythematosus Living With Lupus Donald Thomas, MD, FACP, FACR Author of. All SLE patients should take Plaquenil The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Plaquenil and sle Hydroxychloroquine Reviews Everyday Health, Hydroxychloroquine - Wikipedia Plaquenil for erosive osteoarthritis INTRODUCTION Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Hydroxychloroquine in systemic lupus erythematosus SLE.. Systemic Lupus Erythematosus Living With Lupus. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Systemic lupus erythematosus SLE is a chronic, autoimmune, inflammatory disease characterized by the presence of a plethora of autoantibodies, immune complex formation, and multiple organ system involvement. Gastrointestinal GI manifestations are common in SLE patients, but acute pancreatitis is rare 1–6. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Systemic Lupus Erythematosus. 400 mg 310 mg base PO once or twice daily; maintenance 200-400 mg 155-310 mg base PO daily. Physicians prescribe hydroxychloroquine to treat systemic lupus erythematosus SLE, and it has been shown to have anti-thrombotic effects in SLE patients. Although obvious reasons exist to believe hydroxychloroquine may be useful to treat APS, its use in APS patients remains controversial.